AOA - OMED Research Posters 2024-OMED24-POSTERS

Video Transcription

Video Summary

The research explores the link between methylene tetrahydrofolate reductase (MTHFR) gene variations and autism spectrum disorder (ASD) severity. The study analyzed 78 patients from the RISN Center, showing a significant negative correlation between MTHFR activity and ASD severity. Lower MTHFR activity, impacted by C677T and A1298C mutations, is associated with more severe ASD symptoms. Statistical analyses confirmed these findings, with notable differences in severity levels. The study highlights the importance of genetic factors in ASD and suggests considering MTHFR variations for better diagnostics and treatment. Further research is needed to explore broader behavioral implications.

Keywords

MTHFR gene

autism spectrum disorder

ASD severity

genetic factors

C677T and A1298C mutations