AOA-OMED Research Posters 2024-OMED24-POSTERS

Video Transcription

Video Summary

Jesse Cao, a medical student, presents a study on thalamic neuronal activity in mice, exploring the impacts of transcranial direct stimulation (TDCS) on motor coordination pathways disrupted in spinal cerebellar ataxia. The study uses electrode recordings and DeepLabCut software to analyze thalamic activity during reaching behavior in mice. Results demonstrate a statistically significant change in thalamic neuron firing rates pre- and post-TDCS, highlighting its potential therapeutic benefits for restoring motor functions in ataxia. Future research aims to include more data and ataxic mice to further validate TDCS effectiveness.

Keywords

thalamic neuronal activity

transcranial direct stimulation

spinal cerebellar ataxia

motor coordination pathways

DeepLabCut software