AOA-OMED Research Posters 2024-OMED24-POSTERS

Video Transcription

Video Summary

Emily McKinney's presentation explores the role of oxytocin and its receptor in human parturition, focusing on its immunomodulatory effects at the maternal-fetal interface. Using fetal membrane samples and IDAC cell lines, her research indicates that oxytocin has an anti-inflammatory effect by inhibiting IL-1 beta-induced IL-8 expression. This suggests oxytocin's role in managing the inflammation associated with labor, highlighting its potential clinical applications for labor induction and postpartum hemorrhage management. This research offers insights into maintaining fetal membrane quiescence and the oxytocin system's complex balance during pregnancy.

Keywords

oxytocin

parturition

immunomodulatory

inflammation

pregnancy