Applying Guideline-Directed Care For Patients With T2D: Focus on Glucagon-Like Peptide-1 Receptor Agonists-339095

Video Transcription

Video Summary

The webcast on managing type 2 diabetes focuses on the utilization and benefits of GLP-1 receptor agonists. Dr. Jay Schubert and Dr. Kathleen Dungan discuss guideline-directed care approaches for type 2 diabetes, highlighting the effectiveness of GLP-1 agonists in lowering glucose levels and providing extraglycemic benefits such as weight management and cardiovascular health. Despite advances in diabetes treatment, the glycemic control remains stagnant, which necessitates improved treatment utilization. The incretin system, particularly GLP-1 and GIP hormones, plays a crucial role in glucose metabolism and stimulates insulin secretion in a glucose-dependent manner, thus minimizing the risk of hypoglycemia.<br /><br />GLP-1 receptor agonists offer comprehensive benefits beyond glycemic control, potentially impacting conditions like cardiovascular and kidney diseases. They are shown to effectively promote weight loss and manage type 2 diabetes' complex pathophysiology involving the brain, gut, and islet cells. The webcast emphasizes practical management of side effects, particularly gastrointestinal issues, through patient education and a patient-centered approach, stressing the importance of slow dose escalation.<br /><br />Through case studies, the presenters illustrate the integration of GLP-1 receptor agonists into a comprehensive diabetes management plan that includes lifestyle changes and addressing comorbid conditions like mental health, chronic kidney disease, and socioeconomic factors. The program advocates for the osteopathic approach, combining holistic care principles with evidence-based pharmacotherapy, to effectively manage type 2 diabetes and improve patient outcomes.

Keywords

type 2 diabetes

GLP-1 receptor agonists

guideline-directed care

glucose control

weight management

cardiovascular health

incretin system

insulin secretion

hypoglycemia risk

patient education

comprehensive management

holistic care